منابع مشابه
Phenotypes contribute to treatments.
Chronic obstructive pulmonary disease (COPD) is now considered a markedly complex and heterogeneous disease [1]. In the latest update of the Global Initiative for Chronic Obstructive Lung Disease (GOLD 2017) [2], the definition of COPD has been revised to emphasise the heterogeneity of this disease. The phrase “airway and/or alveolar abnormalities” replaces “an enhanced chronic inflammation” in...
متن کاملTandem duplications contribute to not one but two distinct phenotypes.
Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on th...
متن کاملDistinct macrophage phenotypes contribute to kidney injury and repair.
The ischemically injured kidney undergoes tubular cell necrosis and apoptosis, accompanied by an interstitial inflammatory cell infiltrate. In this study, we show that iNos-positive proinflammatory (M1) macrophages are recruited into the kidney in the first 48 hours after ischemia/reperfusion injury, whereas arginase 1- and mannose receptor-positive, noninflammatory (M2) macrophages predominate...
متن کاملPhenotypes and New Treatments for Severe Asthma
1UGC Allergy, Hospital General de Málaga, Málaga, Spain 2Department of Allergy, Hospital Universitario Marqués de Valdecilla, Santander, Spain 3Allergy Section, Hospital Infantil Universitario Niño Jesús, Madrid, Spain 4Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain 5Department of Allergy, Hospital Universitario Dr. Peset, Valencia, Spain 6Departmen...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2017
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.00054-2017